Optometry and Visual Neuroscience Laboratory
Optometry Department
National School of Higher Education, Leon Unit-UNAM
At @VisNeuroscLab (neur-opht-research.com) you can explore the realms of ophthalmological, optometry, and neuroscience research, where knowledge meets innovation. Discover a range of services catering to both professionals and the public, including cutting-edge programs and social initiatives. Proudly affiliated with the ENES, UNIDAD LEÓN, UNAM, our institution is committed to advancing science, promoting eye health, and fostering community well-being
Research areas
BASIC
The basic research is focused on developing knowledge as well as providing solutions to various eye diseases that affect the Mexican population.
CLINIC
Our research laboratory and the Optometry Clinic participates continuously developing clinical research protocols
Research on:
-Age-Related Macular Degeneration
-Diabetic Retinopathy
-Macular Diabetic Edema
-Aging
-Alzheimer´s Disease Early Diagnosis
-Metabolic and Transcriptomic analysis in Diabetic Retinopathy
Our Team.
This is your Team section. It's a great place to introduce your team and talk about what makes it special, such as your culture and work philosophy. Don't be afraid to illustrate personality and character to help users connect with your team.
Dr. Luis F. Hernández Zimbrón
Principal Investigator
As the head of research in optometry at ENES, UNAM, León, my focus lies on studying visual alterations in neurodegenerative diseases. I strive to identify ocular biomarkers for early Alzheimer's diagnosis. My work extends to translational research on age-related macular degeneration. Additionally, I am responsible for the Institutional Program for Comprehensive Care "No more complications with Diabetes," where we address the needs of prediabetic, type II diabetic, and obese patients in physiotherapy, dentistry, and visual health, aiming for both social impact and research advancement.
ORCID:
https://orcid.org/0000-0002-5098-367X
Dr. Anuar Salazar G
Posdoctoral Fellow (CONAHCYT)
Biotechnology Engineer from the Universidad Politécnica del Estado de Morelos; Master's and Ph.D. in Chemical and Biological Sciences from the Escuela Nacional de Ciencias Biológicas of the IPN. Currently, he is a postdoctoral researcher and adjunct professor in the Optometry degree program at ENES León, UNAM. His scientific experience focuses on preclinical pharmacology of natural products, specifically on the search for active compounds of medicinal interest for the treatment of ocular conditions.
Dr. Manuel Zavala R
Posdoctoral Fellow (CONAHCYT)
Juan Manuel Zavala-Rodríguez is a multifaceted professional with a solid academic background and an outstanding career in the field of optometry and medical research, who combines clinical skills with a firm commitment to the advancement of knowledge in his area of specialization. Zavala-Rodriguez is currently carrying out research using electrophysiological tests and omics strategies for the predictive diagnosis of metabolic diseases as part of a postdoctoral stay with a group of prominent researchers from the National Autonomous University of Mexico.
Hammurabi Flores
Hammurabi Flores, a student of Optometry at the ENES UNAM León, Coordinator of Optometry at Medical Brigadiers of the Bajío, current Municipal Youth Award winner in Health and Prevention, and president of Lentes con Causa (Glasses with a Cause), a project dedicated to spreading awareness and providing visual health services to vulnerable populations.
More info: https://www.instagram.com/p/Cv09liRO_-A/?igsh=MWlqdHRxYjdkMzY2ZA%3D%3D
A Sight to See
Corneal alkali burn model for evaluation of anti-inflammatory compounds
Our Services
C
Análisis de lágrima
Enseñanza en investigación en Optometría
contacto: opseop@enes.unam.mx o asiste de manera presencial a la Clínica de optometría ENES LEÓN UNAM)
Panel
Vulnerabilidad social y su abordaje en el área de la salud y las humanidades
https://www.facebook.com/watch/live/?ref=watch_permalink&v=2152244595261842&rdid=W6AqZupyLPBZet9t
Salud visual y ladrilleras
Estudiantes y profesores atienden males oculares en comunidad ladrillera
Título aquí
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Videos
Videos informativos de salud visual
https://www.tiktok.com/@eye.of.kepler?_t=ZS-8zfpMsSRm4X&_r=
Reportaje
UNAM detecta afecciones oculares en comunidad ladrillera
LINK a REPORTAJE, da CLICK AQUÍ
(Créditos: Gaceta UNAM, 2025
Título aquí
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Divulgación
Aquí podrás encontrar las diferentes actividades de difusión o divulgación que realizamos
Our latest publications
Rodríguez-Arzate, C. A., Noguez-Imm, R., Reyes-Ortega, P., Rodríguez-Ortiz, L. R., García-Peña, M. F., Ordaz, R. P., ... & Thébault, S. C. (2024). Potential contributions of the intrinsic retinal oscillations recording using non-invasive electroretinogram to bioelectronics. Frontiers in Cellular Neuroscience, 17, 1224558.
Hernández, E. R., Zimbrón, L. F. H., Pérez, E. S., Salgado, J. L. S., Morales, M. A. P., & Zenteno, E. (2024). Galectin-9 and Tim-3 are upregulated in response to microglial activation induced by the peptide Amyloid-β (25–35). Neuropeptides, 102426.ed Tech
Salazar-Gómez, A., Velo-Silvestre, A. A., Alonso-Castro, A. J., & Hernández-Zimbrón, L. F. (2023). Medicinal plants used for eye conditions in mexico—A review. Pharmaceuticals, 16(10), 1432.
"A novel and functional Artificial Bruch's Membrane made of Poly (ε-caprolactone)/Gelatin for Retinal Pigment Epithelium Restoration" (has been accepted for publication.)
Noguez Imm, R., Muñoz-Benitez, J., Medina, D., Barcenas, E., Molero-Castillo, G., Reyes-Ortega, P., ... & Thébault, S. C. (2023). Preventable risk factors for type 2 diabetes can be detected using noninvasive spontaneous electroretinogram signals. PLoS One, 18(1), e0278388.
ONGOING STUDENT RESEARCH PROJECTS
1. Análisis del grosor macular central, nivel lipídico y glucémico, agudeza visual y respuesta en electrorretinograma en pacientes sanos, prediabéticos, con síndrome metabólico y diabéticos
2. Contaminación por partículas de aire, neurotoxicidad y diabetes: efectos y mecanismos para los riesgos en salud visual en el sector ladrillero
3. Estudio de la correlación entre el perfil metabolómico sérico, las señales del electrorretinograma basal y la expresión génica en personas con riesgo de desarrollar diabetes tipo 2: impacto de la actividad física.
4. Estudio del efecto de la savia de tres especies del género Sedum sobre la expresión de mediadores inflamatorios y su potencial uso en la prevención y tratamiento del síndrome del ojo seco.
5. Biomarcadores inflamatorios de segmento anterior en pacientes con diabetes
6. Detección de péptidos amiloides de la superficie ocular en pacientes con enfermedades neurodegenerativas.
7. Evaluación de percepción visual y visión al color en personas con enfermedades neurodegenerativas
8. Programa Institucional de Atención Integral No mas complicaciones con la diabetes
Facilities
CONTACT
Address
Blv. UNAM #2011, Predio El Saucillo y, Comunidad de los Tepetates, El Potrero, 37684 León, Gto
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